(1)

Registration Statement (Form S-8 No. 333-152669) pertaining to the 2008 Stock Incentive Plan of Idera Pharmaceuticals, Inc.

(2)

Registration Statement (Form S-8 No. 333-176067) pertaining to the 2008 Stock Incentive Plan and 1995 Employee Stock Purchase Plan of Idera Pharmaceuticals, Inc.

(3)

Registration Statement (Form S-8 No. 333-191076) pertaining to the 2013 Stock Incentive Plan of Idera Pharmaceuticals, Inc.

(4)

Registration Statement (Form S-8 No. 333-197062) pertaining to the 2013 Stock Incentive Plan of Idera Pharmaceuticals, Inc.

(5)

Registration Statement (Form S-8 No. 333-202691) pertaining to Inducement Stock Option Awards of Idera Pharmaceuticals, Inc.

(6)

Registration Statement (Form S-8 No. 333-206129) pertaining to the 2013 Stock Incentive Plan, as amended, of Idera Pharmaceuticals, Inc.

(7)

Registration Statement (Form S-8 No. 333-210090) pertaining to an Inducement Stock Option Award of Idera Pharmaceuticals, Inc.

(8)

Registration Statement (Form S-1 as amended by Form S-3/A No. 333-136610) of Idera Pharmaceuticals, Inc.

(9)

Registration Statement (Form S-1 as amended by Form S-3/A No. 333-187155) of Idera Pharmaceuticals, Inc.

(10)

Registration Statement (Form S-2 as amended by Form S-3/A No. 333-109630) of Idera Pharmaceuticals, Inc.

(11)

Registration Statement (Form S-3 No. 333-119943) of Idera Pharmaceuticals, Inc.

(12)

Registration Statement (Form S-3 No. 333-126634) of Idera Pharmaceuticals, Inc.

(13)

Registration Statement (Form S-3 No. 333-131804) of Idera Pharmaceuticals, Inc.

(14)

Registration Statement (Form S-3 No. 333-133455) of Idera Pharmaceuticals, Inc.

(15)

Registration Statement (Form S-3 No. 333-133456) of Idera Pharmaceuticals, Inc.

(16)

Registration Statement (Form S-3 No. 333-139830) of Idera Pharmaceuticals, Inc.

(17)

Registration Statement (Form S-3 as amended by Form S-3/A No. 333-185392) of Idera Pharmaceuticals, Inc.

(18)

Registration Statement (Form S-3 No. 333-186312) of Idera Pharmaceuticals, Inc.

(19)

Registration Statement (Form S-3 No. 333-189700) of Idera Pharmaceuticals, Inc.

(20)

Registration Statement (Form S-3 No. 333-210140) of Idera Pharmaceuticals, Inc.

(21)

Registration Statement (Form S-8 No. 333-217665) pertaining to an Inducement Stock Option Award of Idera Pharmaceuticals, Inc.

(22)

Registration Statement (Form S-8 No. 333-219740) pertaining to the 2017 Employee Stock Purchase Plan of Idera Pharmaceuticals, Inc.

(23)

Registration Statement (Form S-8 No. 333-219741) pertaining to the 2013 Stock Incentive Plan, as amended, of Idera Pharmaceuticals, Inc.

(24)

Registration Statement (Form S-8 No. 333-232609) pertaining to the 2017 Employee Stock Purchase Plan of Idera Pharmaceuticals, Inc.

(25)

Registration Statement (Form S-8 No. 333-232610) pertaining to the 2013 Stock Incentive Plan, as amended, of Idera Pharmaceuticals, Inc.

(26)

Registration Statement (Form S-3 No. 333-238868) of Idera Pharmaceuticals, Inc.

(27)

Registration Statement (Form S-3 No. 333-240361) of Idera Pharmaceuticals, Inc.

(28)

Registration Statement (Form S-3 No. 333-240366) of Idera Pharmaceuticals, Inc.

(29)

Registration Statement (Form S-3 No. 333-248560) of Idera Pharmaceuticals, Inc.

(30)

Registration Statement (Form S-3 and S-3/A No. 333-253804) of Idera Pharmaceuticals, Inc.