Exhibit 99.2

Renalytix plc

(“Renalytix” or the “Company”)

Directorate Change

LONDON and NEW YORK, 31 October 2024 – Renalytix plc (LSE: RENX) (OTCQB: RNLXY), an artificial intelligence-enabled in vitro diagnostics company, focused on optimizing clinical management of kidney disease to drive improved patient outcomes and advance value-based care, announces that Dan Levangie, Non-Executive Director has stepped down from the Board of Renalytix, effective immediately, following the General Meeting today.

James McCullough, CEO of Renalytix plc, commented: “We would like to express our gratitude to Dan for all of his contributions to Renalytix during a very significant period for the business. Dan’s counsel through these past years has been invaluable as we have conducted a successful turn-around and refinancing of Renalytix and expanded our commercial introduction of KidneyIntelX for early prognosis of chronic kidney disease.”

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About Renalytix

Renalytix (NASDAQ: RNLX) (LSE: RENX) is an in-vitro diagnostics and laboratory services company that is the global founder and leader in the new field of bioprognosis™ for kidney health. The leadership team, with a combined 200+ years of healthcare and in-vitro diagnostic experience, has designed its KidneyIntelX laboratory developed test to enable risk assessment for rapid progressive decline in kidney function in adult patients with T2D and early CKD (stages 1-3). We believe that by understanding how disease will progress, patients and providers can take action early to improve outcomes and reduce overall health system costs.

For more information, visit www.renalytix.com