Exhibit 23.1

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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

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We consent to the incorporation by reference in the Registration Statements on Form S-8 (No. 333-272894), and Form S-3 (Nos. 333-279231 and 333-259303) of ReShape Lifesciences Inc. (the “Company”) of our report dated April 4, 2025, relating to the consolidated financial statements as of December 31, 2024 and for the year then ended, which appears in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024.

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Our report includes an explanatory paragraph expressing substantial doubt regarding the Company’s ability to continue as a going concern.

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