Subsidiary

Jurisdiction

Globus Medical North America, Inc.

Pennsylvania

Branch Medical Group, LLC

Delaware

NuVasive, Inc.

Delaware

NuVasive Technology International Limited

Malta

KB Medical SA

Switzerland

Synoste OY

Finland

Nemaris Inc.

Delaware

Globus Medical SARL

Switzerland

MIS Spine Comercials de R.L. de C.V.

Mexico

Globus Medical Brazil LDTA

Brazil

Globus Medical Italy S.r.l

Italy

American Neuromonitoring Associates, P.C.

Maryland

Simplify Medical Pty.

Australia

Globus Medical Netherlands Biologics

Netherlands

NuVasive Netherlands Coopertief U.A.

Netherlands

NuVasive Netherlands B.V.

Netherlands

NuVasive Clinical Services Monitoring Inc.

Delaware

NuVasive Japan K.K.

Japan

NuVasive Specialized Orthopedics, Inc.

Delaware

NuVasive Germany GmbH

Germany

NuVasive Italia S.r.l.

Italy

Globus Medical Japan GK

Japan

NuVasive (AUST/NZ) Pty. Ltd.

Australia