Q1 2025 Financial Results Conference Call May 7th, 2025 Veeco Instruments

Safe Harbor This presentation contains “forward-looking statements”, within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, as amended, that are based on management’s expectations, estimates, projections and assumptions. Words such as “expects,” “anticipates,” “plans,” “believes,” “scheduled,” “estimates” and variations of these words and similar expressions are intended to identify forward-looking statements. Forward-looking statements include, but are not limited to, those regarding anticipated growth and trends in our businesses and markets, industry outlooks and demand drivers, our investment and growth strategies, our development of new products and technologies, our business outlook for current and future periods, our ongoing transformation initiative and the effects thereof on our operations and financial results; and other statements that are not historical facts. These statements and their underlying assumptions are subject to risks and uncertainties and are not guarantees of future performance. Factors that could cause actual results to differ materially from those expressed or implied by such statements include, without limitation: global trade issues, including the effects of foreign and domestic tariffs and the ongoing trade disputes between the U.S. and China, and changes in trade and export license policies; the level of demand for our products; global economic and industry conditions; global conflicts; our dependency on third-party suppliers and outsourcing partners; the timing of customer orders; our ability to develop, deliver and support new products and technologies; our ability to expand our current markets, increase market share and develop new markets; the concentrated nature of our customer base; cybersecurity attacks and our ability to safeguard sensitive information and protect our intellectual property rights in key technologies; the effects of regional or global health epidemics; our ability to achieve the objectives of operational and strategic initiatives and attract, motivate and retain key employees; the variability of results among products and end-markets, and our ability to accurately forecast future results, market conditions, and customer requirements; the impact of our indebtedness, including our convertible senior notes and our capped call transactions; and other risks and uncertainties described in our SEC filings on Forms 10-K, 10-Q and 8-K, and from time-to-time in our other SEC reports. All forward-looking statements speak only to management’s expectations, estimates, projections and assumptions as of the date of this presentation. The Company does not undertake any obligation to update or publicly revise any forward-looking statements to reflect events, circumstances or changes in expectations after the date of this presentation.

Bill Miller, Ph.D. CEO Overview

Q1 2025 Highlights • Revenue above mid-point of guidance, EPS above guidance • Another strong quarter for Semi business, grows sequentially and year-over-year • Growth driven by wet processing and lithography system shipments in Advanced Packaging • Shipped several LSA systems for Gate-all-around (GAA) and High-Bandwidth-Memory (HBM) • Several key wins reflecting progress on long-term strategy • Awarded Intel’s 2025 EPIC Supplier Award • LSA system orders for GAA and HBM • LSA system named Production Tool of Record at two leading-edge customers for new applications • Wet processing system qualified at IDM for two new applications Revenue $167M Non-GAAP Operating Income $24M Diluted Non-GAAP EPS 0.37¢ Strong quarter from Semiconductor business and several key strategic wins

Role in the Semi Manufacturing Deposition Lithography Ion Implantation Etch Annealing Inspection/ Metrology Advanced Packaging IBD 300 IBD EUV LSA NSA Wet Processing Litho New products FRONT END BACK END Driving business today Representative Process Steps Veeco technologies are critical for several Semi manufacturing process steps IBD – Ion Beam Deposition EUV – Extreme ultraviolet LSA- Laser Spike Annealing NSA – Nanosecond Annealing

Semi SAM Expansion To Drive Outperformance Markets Industry Inflections Advanced Logic GAA/BSPD Device Shrink - EUV/High NA Lithography Memory HBM/3D Devices Advanced Packaging 3D Packaging For AI Heterogeneous Integration LSA NSA IBD 300 Wet Processing IBD EUV 0% 5% 10% 15% 20% 2025-2029 CAGR WFE Growth Veeco Semi SAM Enabling Technologies Enabling technologies for industry inflections provide opportunity to outperform WFE growth *WFE CAGR based on Tech Insights Long-Term Semiconductor, Silicon, and Equipment forecast, Veeco Semi SAM CAGR based on TrendFocus, Gartner, Yole Group and internal analysis. * BSPD – Backside Power Delivery

Semi Evaluations Capture Industry Inflections Increase in evaluations to enable penetration of key SAM growth opportunities *Evaluations typically compete to win several applications. The number of applications under evaluation will vary by system, customer, and market.

John Kiernan CFO Financial Overview

Q1 Revenue by Market & Region Revenue by Market Revenue by Region Scientific & Other Semiconductor Compound Semiconductor Data Storage EMEA APAC China United States $167M Revenue Trend ($M) Q1 24 Q4 24 Q1 25 Semiconductor 120 112 124 Compound Semi 21 23 14 Data Storage 18 14 7 Scientific & Other 15 33 22 Total 174 182 167 Amounts may not calculate precisely due to rounding. ROW is negligible 9% 4% 13% 74% 36% 15% 7% 42% United States China APAC EMEA Revenue Trend ($M) Q1 24 Q4 24 Q1 25 China 64 71 71 APAC 73 56 60 USA 28 35 24 EMEA & ROW 8 20 12 Total 174 182 167

In millions (except per share amounts) GAAP Non-GAAP Q4 24 Q1 25 Q4 24 Q1 25 Revenue $182.1 $167.3 $182.1 $167.3 Gross Profit 74.0 68.5 75.5 69.8 Gross Margin 40.6% 40.9% 41.5% 41.7% Operating Expenses 70.1 54.3 48.1 45.5 Operating Income 3.9 14.2 27.4 24.3 Net Income 15.0 11.9 24.2 22.2 Diluted Earnings Per Share 0.26 0.20 0.41 0.37 Diluted Shares 60.5 60.2 60.1 60.0 Amounts may not calculate precisely due to rounding. A reconciliation of GAAP to Non-GAAP financial measures can be found in the backup section of this presentation. Q1 Operating Results

Amounts may not calculate precisely due to rounding. A reconciliation of GAAP to Non-GAAP financial measures can be found in the backup section of this presentation. Balance Sheet and Cash Flow Highlights $ millions Q4 24 Q1 25 Cash & Short-Term Investments 345 353 Accounts Receivable 97 114 Inventories 247 254 Accounts Payable 44 58 Cash Flow from Operations 28 20 Capital Expenditures 5 7 DSO (days) 48 62 DIO (days) 203 228 DPO (days) 37 53

Q2 2025 Outlook A reconciliation of GAAP to Non-GAAP financial measures can be found in the backup section of this presentation. GAAP Non-GAAP Revenue $135M - $165M $135M - $165M Gross Margin 39%-41% 40%-42% Operating Expenses $57M - $58M $47M - $48M Net Income $(3M) - $10M $7M - $20M Diluted Earnings Per Share $(0.05) - $0.17 $0.12 - $0.32

Q&A

Backup & Financial Tables

Historical Revenue by End-Market Amounts may not calculate precisely due to rounding. $M 2021 2022 2023 2024 2025 FY Q1 Q2 Q3 Q4 FY Q1 Q2 Q3 Q4 FY Q1 Q2 Q3 Q4 FY Q1 Semi 247.1 77.6 97.5 100.4 93.8 369.4 93.1 106.3 98.2 115.2 412.7 120.4 109.9 124.1 112.1 466.6 123.8 Compound Semi 107.0 37.1 31.1 28.1 24.9 121.2 21.2 24.1 25.7 16.3 87.3 21.0 18.2 15.6 22.8 77.6 14.4 Data Storage 168.8 21.6 21.5 27.7 16.7 87.5 21.5 13.9 34.0 19.1 88.5 18.0 34.0 32.8 14.1 98.9 6.7 Scientific & Other 60.5 20.1 13.8 15.7 18.4 68.0 17.7 17.4 19.6 23.4 78.0 15.1 13.8 12.4 33.0 74.2 22.4 Total 583.3 156.4 164.0 171.9 153.8 646.1 153.5 161.6 177.4 173.9 666.4 174.5 175.9 184.8 182.1 717.3 167.3

Convertible Notes – Outstanding * Conversion price for 2027 Convertible Notes includes the effect of the Capped Call transaction **Weighted average Convertible Notes Principal Amount Carrying Value Coupon Annual Cash Interest Annual Non-Cash Interest Initial Conversion Price Convertible Notes Due June 2027 25M 25M 3.75% 0.9M 0.1M 18.46* Convertible Notes Due June 2029 230M 225M 2.875% 6.6M 1.1M 29.22 Total Convertible Notes $255M $250M 2.96%** $7.5M $1.2M $28.17** As of March 31, 2025

Effect of Convertible Notes on Diluted EPS (Effective Q1 2025) Based upon current 2027 Convertible Notes outstanding. The above calculations are intended to be estimates only, and reflect the use of the if-converted method for diluted EPS purposes. The EPS thresholds mentioned above represent various ranges at which some of our Convertible Notes may become dilutive. No shares are added for dilution purposes if the addition of such shares (and reduced interest expense) would be anti-dilutive. * The non-GAAP incremental dilutive shares includes the impact of the Company’s capped call transactions issued concurrently with our 2027 Convertible Notes, and assumes an average per share stock price above $18.46. ** The Company is required to settle the principal amount of the 2029 Convertible Notes in cash, and has the option to settle the excess above principal in any combination of cash or shares. As such, only “in-the-money” shares above the implied conversion price of $29.22 are added to the diluted share count, and there is no interest expense add-back to the numerator for purposes of calculating diluted EPS. 2027 Convertible Notes Quarterly GAAP Non-GAAP* EPS threshold before effect of Notes Reduction to Interest expense for EPS calculation (in thousands) Incremental Dilutive Shares** (in thousands) EPS threshold before effect of Notes Reduction to Interest expense for EPS calculation (in thousands) Incremental Dilutive Shares** (in thousands) > $0.14 $257 1,788 > $0.17 $234 1,354 Annual GAAP Non-GAAP* EPS threshold before effect of Notes Reduction to Interest expense for EPS calculation (in thousands) Incremental Dilutive Shares** (in thousands) EPS threshold before effect of Notes Reduction to Interest expense for EPS calculation (in thousands) Incremental Dilutive Shares** (in thousands) ≥ $0.57 $1,100 1,788 ≥ $0.69 $1,000 1,354 2029 Convertible Notes (GAAP and Non-GAAP)** Average Stock Price per Common Share Incremental Dilutive Shares (in thousands) $29.00 - $30.00 205 $31.00 452 $32.00 684 $33.00 902 $34.00 1,106 $35.00 1,300 $36.00 1,482 $37.00 1,655 $38.00 1,818 $39.00 1,974 $40.00 2,121 $41.00 2,261 $42.00 2,395 $43.00 2,522 $44.00 2,644 $45.00 2,760

Note on Reconciliation Tables These tables include financial measures adjusted for the impact of certain items; these financial measures are therefore not calculated in accordance with U.S. generally accepted accounting principles (“GAAP”). These Non-GAAP financial measures exclude items such as: share-based compensation expense; charges relating to restructuring initiatives; non-cash asset impairments; certain other non-operating gains and losses; and acquisition-related items such as transaction costs, non-cash amortization of acquired intangible assets, incremental transaction-related compensation, and certain integration costs. These Non-GAAP financial measures may be different from Non-GAAP financial measures used by other companies. Non-GAAP financial measures should not be considered a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP. By excluding these items, Non-GAAP financial measures are intended to facilitate meaningful comparisons to historical operating results, competitors' operating results, and estimates made by securities analysts. Management is evaluated on key performance metrics including Non-GAAP Operating Income, which is used to determine management incentive compensation as well as to forecast future periods. These Non-GAAP financial measures may be useful to investors in allowing for greater transparency of supplemental information used by management in its financial and operational decision-making. In addition, similar Non-GAAP financial measures have historically been reported to investors; the inclusion of comparable numbers provides consistency in financial reporting. Investors are encouraged to review the reconciliation of the Non-GAAP financial measures used in this news release to their most directly comparable GAAP financial measures.

Amounts may not calculate precisely due to rounding. Supplemental Information—GAAP to Non-GAAP Reconciliation $ millions Q4 24 Q1 25 Net sales $182.1 $167.3 GAAP gross profit 74.0 68.5 GAAP gross margin 40.6% 40.9% Add: Share-based comp 1.5 1.3 Non-GAAP gross profit $75.5 $69.8 Non-GAAP gross margin 41.5% 41.7% In millions Q4 24 Q1 25 GAAP Net income $15.0 $11.9 Add: Share-based comp 9.1 9.2 Add: Amortization 1.6 0.8 Add: Asset impairment 28.1 - Add: Changes in contingent consideration (16.5) - Add: Other 1.2 0.1 Add: Interest expense (income) (0.5) (0.8) Add: Tax expense (benefit) (10.6) 3.0 Non-GAAP operating income $27.4 $24.3 $ millions, except per share amounts Q4 24 Q1 25 GAAP Basic weighted average shares 56.5 57.8 GAAP Diluted weighted average shares 60.5 60.2 GAAP Basic EPS $0.26 $0.21 GAAP Diluted EPS $0.26 $0.20 GAAP Net income $15.0 $11.9 Add: Share-based comp 9.1 9.2 Add: Amortization 1.6 0.8 Add: Asset impairment 28.1 - Add: Changes in contingent consideration (16.5) - Add: Other 1.2 0.1 Add: Non-cash interest expense 0.3 0.3 Add: Tax benefit associated with asset impairments (12.2) - Add: Tax adjustment from GAAP to Non-GAAP (2.4) (0.1) Non-GAAP net income 24.2 22.2 Non-GAAP basic EPS $0.43 $0.38 Non-GAAP diluted EPS $0.41 $0.37 Non-GAAP basic weighted average shares 56.5 57.8 Non-GAAP diluted weighted average shares 60.1 60.0 In millions Q4 24 Q1 25 GAAP operating expenses $70.1 $54.3 Share-based compensation (7.6) (7.9) Amortization (1.6) (0.8) Other (12.9) (0.1) Non-GAAP operating expenses $48.1 $45.5

$ millions Non-GAAP Adjustments GAAP Share-Based Compensation Amortization Other Non-GAAP Net Sales $167.3 $167.3 Gross Profit 68.5 1.3 — — 69.8 Gross Margin 40.9% 41.7% Operating Expenses $54.3 (7.9) (0.8) (0.1) $45.5 Operating Income $14.1 9.2 0.8 0.1 $24.3 Net Income $11.9 9.2 0.8 0.2 $22.2 Q1 2025 Actual: GAAP to Non-GAAP Reconciliation Amounts may not calculate precisely due to rounding. Income per Diluted Common Share GAAP Non-GAAP Net Income $11.9 $22.2 Add: Interest on Convertible Senior Notes 0.3 0.3 Net income available to common shareholders 12.2 22.5 Basic weighted average common shares 57.8 57.8 Add: Dilutive effect of share-based awards 0.7 0.7 Add: Dilutive effect of 2025 Convertible Senior Notes - 0.2 Add: Dilutive effect of 2027 Convertible Senior Notes 1.8 1.4 Diluted weighted average common shares 60.2 60.0 Basic income per common share $0.21 $0.38 Diluted income per common share $0.20 $0.37 Other Non-GAAP Adjustments Other 0.1 Subtotal 0.1 Non-cash Interest Expense 0.3 Non-GAAP tax adjustment (0.1) Total Other $0.2

Reconciliation of GAAP to non-GAAP Financial Data Non-GAAP Adjustments GAAP Share-Based Compensation Amortization Other Non-GAAP Net Sales $135–$165 $135–$165 Gross Profit 54–69 1 — — 55–70 Gross Margin 39%–41% 40%–42% Operating Expenses $57–$58 (9) (1) — $47–$48 Operating Income (loss) ($3)–$11 10 1 — $8–$22 Net Income (loss) ($3)–$10 10 1 (1) $7–$20 Income (loss) per Diluted Share ($0.05)–$0.17 $0.12–$0.32 Q2 2025 Guidance ($ millions, except per share amounts) Amounts may not calculate precisely due to rounding. Income per Diluted Common Share GAAP Non-GAAP Net income (loss) available to common shareholders ($3)–$10 $7–$20 Basic weighted average common shares 58 58 Add: Dilutive effect of share-based awards 0-1 1-1 Add: Dilutive effect of 2027 Convertible Senior Notes 0-2 0-1 Diluted weighted average common shares 58-61 59-61 Income per diluted common share ($0.05)-$0.17 $0.12-$0.32 Reconciliation of GAAP Net Income to non-GAAP Operating Income GAAP Net Income (loss) ($3)–$10 Share-Based Compensation 10 Amortization 1 Interest income (1) Income tax expense 0-1 Non-GAAP Operating Income $8–$22